Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8835606 | Journal of Surgical Research | 2018 | 11 Pages |
Abstract
DNA in the tumor microenvironment promotes survival through induction of autophagy via TLR-9 signaling. This work has important implications for targeting extracellular DNA, TLR-9, and autophagy during treatment with chemotherapy and enhances our understanding of the role of extracellular DNA in the tumor microenvironment.
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Authors
Reginald MD, Brian A. MD, Nick BS, Daolin MD, PhD, Rui MD, PhD, Tara MD, Michael T. MD, Herbert J. MD,