Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8835700 | Journal of Surgical Research | 2018 | 8 Pages |
Abstract
We concluded that cisplatin or vincristine could enhance liver metastasis of mouse melanoma cells or human neuroblastoma cells, respectively. In addition, the mRNA expression of MMP-2 and periostin, or MMP-9 and S100A8/9 is increased by cisplatin or vincristine pretreatment, possibly resulting in fibrosis or neutrophil recruitment, respectively. These niche factors might be associated with increased liver metastasis.
Keywords
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Authors
Masahiro MD, PhD, Takashi MD, PhD, Hiroshi MD, PhD, Toru MD, PhD, Shuichiro MD, PhD, Mikiya MD, PhD, Hiroomi MD, PhD, Kenji MD,