Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8835853 | Journal of Surgical Research | 2018 | 8 Pages |
Abstract
Slit3 KO mice with CDH show evidence of PAH and resultant RV dilation. Using direct cardiac puncture, elevated RV systolic pressures have been demonstrated in KO mice as evidence of PAH. Echocardiography allows direct analysis of the PA and real-time RV function without sacrifice of the mouse. This mode of evaluation allows longitudinal study in mice with PAH and CDH.
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Authors
Mansi MD, Michael R. MD, Megan MD, Gary RDCS, Sean E. MD,