Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8836920 | Surgery | 2018 | 5 Pages |
Abstract
Principal component analysis detects 3 patterns of coagulation dysregulation using widely available laboratory parameters: (1) abnormalities in clot strength; (2) abnormalities in fibrinolysis, and (3) clotting factor depletion. While all were associated with mortality and transfusion, fibrinolytic dysregulation was associated with injury severity and portends particularly poor outcome including venous thromboembolism and disability.
Related Topics
Health Sciences
Medicine and Dentistry
Surgery
Authors
Christine M. Leeper, Matthew D. Neal, Christine McKenna, Timothy Billiar, Barbara A. Gaines,