| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8837096 | Surgery | 2018 | 6 Pages |
Abstract
Substantial reversal of tumor-derived immunosuppression may be achieved by blocking Interleukin-10 in the local microenvironment, allowing for more effective cytotoxicity of mesothelin-engrafted chimeric antigen receptor T cells and enhancing the potential for clinical application.
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Authors
Ramesh B. Batchu, Oksana V. Gruzdyn, Ebrahem M. Mahmud, Fatme Chukr, Rajesh Dachepalli, Santosh K. Manmari, Gamal Mostafa, Donald W. Weaver, Scott A. Gruber,