| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8837476 | Surgery | 2016 | 9 Pages |
Abstract
pmTOR expression is an indicator of aggressive, metastatic papillary thyroid carcinoma, being possibly implicated in refractoriness to therapy, while pS6 expression is associated with less aggressive pathologic features. Further studies are needed to understand better the biologic consequences of activation of the mTOR pathway in the behavior of thyroid cancer, namely the contribution of other pmTOR downstream effectors.
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Authors
Catarina DVM, Maria João MSc, Miguel MD, PhD, Adriana Gaspar MD, Ana MSc, Rui MSc, Catarina MSc, Catarina MD, PhD, Luciana MSc, Elisabete MD, Manuel MD, PhD, Paula PhD,