Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8837840 | Behavioural Brain Research | 2018 | 4 Pages |
Abstract
It is well known that stress affects memory performance. However, there still appears to be inconstancy in literature about how acute stress affects the different stages of memory: acquisition, consolidation and retrieval. In this study, we exposed rats to acute stress and measured the effect on memory performance in the object recognition task as a measure for episodic memory. Stress was induced 30â¯min prior to the learning phase to affect acquisition, directly after the learning phase to affect consolidation, or 30â¯min before the retrieval phase to affect retrieval. Additionally, we induced stress both 30â¯min prior to the learning phase and 30â¯min prior to the retrieval phase to test whether the effects were related to state-dependency. As expected, we found that acute stress did not affect acquisition but had a negative impact on retrieval. To our knowledge, we are the first to show that early consolidation was negatively affected by acute stress. We also show that stress does not have a state-dependent effect on memory.
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Authors
Ellis Nelissen, Jos Prickaerts, Arjan Blokland,