| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8838613 | International Journal of Epilepsy | 2017 | 9 Pages |
Abstract
According to the corresponding findings depending on concentrations both drugs incorporate into phosphatidylcholines, perturbing the packing of lipids and affecting their thermotropic properties. Their binding affinity to acyl chains and hydrophilic parts of lipids was found to highly correlate with lipid-water partition and their solubility degree in water. Hence, the obtained results may offer evaluation of partition profile of the drugs into biological membranes depending on concentration.
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Authors
Sevgi Türker-Kaya, Aygül Kına, Selen Alın,