Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8838909 | Brain Research Bulletin | 2018 | 55 Pages |
Abstract
T2DM has a negative impact on cognitive functions through different pathological and subcellular mechanisms. The current study provides evidence for involvement of BDNF and brain Visfatin in T2DM- associated cognitive dysfunction. BDNF and brain Visfatin were also found to contribute to the neuro-protective effect of Ex-4 via modulation of inflammation, oxidative stress, neuro-degeneration and synaptic function.
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Authors
O.M. Abdelwahed, O.M. Tork, M.M. Gamal el Din, L. Rashed, M. Zickri,