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The physiological and pathological biophysics of phase separation and gelation of RNA binding proteins in amyotrophic lateral sclerosis and fronto-temporal lobar degeneration

Article ID Journal Published Year Pages File Type
8839742 Brain Research 2018 41 Pages PDF
Keywords
PTMRGGDDX4SMNPY-NLSRRMFTLDTAF15TDP-43hnRNPEWSFUsRNA recognition motifamyotrophic lateral sclerosisfamilial amyotrophic lateral sclerosispost-translational modificationCHOPPhase separationfALSfrontotemporal lobar degenerationheterogeneous nuclear ribonucleoproteinfrontotemporal dementiaArginine methylationsurvival motor neuronRNA binding proteins
Related Topics
Life Sciences Neuroscience Neuroscience (General)
Preview
The physiological and pathological biophysics of phase separation and gelation of RNA binding proteins in amyotrophic lateral sclerosis and fronto-temporal lobar degeneration
Authors
Peter St George-Hyslop, Julie Qiaojin Lin, Akinori Miyashita, Emma C. Phillips, Seema Qamar, Suzanne J. Randle, GuoZhen Wang,
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Journal
Brain Research
Journal: Brain Research
Related Categories
PTM
RGG
DDX4
SMN
PY-NLS
RRM
FTLD
TAF15
TDP-43
hnRNP
EWS
FUs
RNA recognition motif
amyotrophic lateral sclerosis
familial amyotrophic lateral sclerosis
post-translational modification
CHOP
Phase separation
fALS
frontotemporal lobar degeneration
heterogeneous nuclear ribonucleoprotein
frontotemporal dementia
Arginine methylation
survival motor neuron
RNA binding proteins
Behavioral Neuroscience
Biological Psychiatry
Cellular and Molecular Neuroscience
Cognitive Neuroscience
Developmental Neuroscience
Endocrine and Autonomic Systems
Neurology
Neuroscience (General)
Sensory Systems
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