Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8840321 | Journal of Neuroscience Methods | 2018 | 11 Pages |
Abstract
The results from this proof-of-concept study support the utility of our repeated intranasal dosing methodology in awake Rhesus macaques, to evaluate the effects of neuroactive compounds on the NHP brain. Additionally, results indicate that DNSP-11 can be safely and effectively delivered intranasally in MPTP-treated NHPs, while engaging the DA system.
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Neuroscience
Neuroscience (General)
Authors
M.J. Stenslik, A. Evans, F. Pomerleau, R. Weeks, P. Huettl, E. Foreman, J. Turchan-Cholewo, A. Andersen, W.A. Cass, Z. Zhang, R.C. Grondin, D.M. Gash, G.A. Gerhardt, L.H. Bradley,