Article ID Journal Published Year Pages File Type
8840456 Journal of Neuroscience Methods 2018 27 Pages PDF
Abstract
Collagen scaffolds loaded with low amounts of a protein/drug of interest can be easily applied directly onto organotypic brain slices, allowing slow targeted release of a protective molecule. Such an approach is highly useful to optimize CollScaff for further in vivo applications.
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Life Sciences Neuroscience Neuroscience (General)
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Nerve growth factor released from collagen scaffolds protects axotomized cholinergic neurons of the basal nucleus of Meynert in organotypic brain slices
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