Maternal High-fat Diet Programs Offspring Emotional Behavior in Adulthood

Article ID	Journal	Published Year	Pages	File Type
8840522	Neuroscience	2018	16 Pages	PDF

Abstract

The present results suggest that neuroinflammatory and stress axis pathways in the hippocampus may contribute to anxiogenic effects of maternal HFD in offspring.

Keywords

FST TNF Kynurenine 3-monooxygenase OGTT NOR OFT HFD EPM LPS IGF MCP PND MIP BDNF NFκB KMO Open field test Oral glucose tolerance test forced swim test Anxiety Depression interleukin con Pregnancy elevated plus maze postnatal day high-fat diet control diet Novel object recognition Insulin-like growth factor Brain-derived neurotrophic factor tumor necrosis factor nuclear factor kappa beta lipopolysaccharide HPA macrophage inflammatory protein monocyte chemoattractant protein Maternal obesity KAT Kynurenine aminotransferase Mineralocorticoid receptor glucocorticoid receptor

Related Topics

Life Sciences Neuroscience Neuroscience (General)

Maternal High-fat Diet Programs Offspring Emotional Behavior in Adulthood

Authors

Gudrun Winther, Betina Elfving, Heidi Kaastrup Müller, Sten Lund, Gregers Wegener,