Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8841335 | Neuroscience Letters | 2018 | 7 Pages |
Abstract
Overall, corticosterone was not significantly affected following acute stress in ketamine-anesthetized rats. Early mortality was primarily due to polytrauma and change in the animal's biochemical parameters appeared at t4 post trauma. The findings indicate that ketamine-anesthesia and/or surgery may have overshadowed the effect of the initial stress.
Keywords
ACTHTBIWBCMC2RHCTTIVAHspCBCTraumatic brain injurypost-traumatic stress disorderPTSDStressMANOVABlastEBVAnesthesiaTotal intravenous anesthesiaMultiple analysis of varianceHemorrhagemean arterial pressuremaphematocritHemoglobinadrenocorticotropic hormoneResponsivenessHeat shock proteinwhite blood cell
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Authors
Françoise Arnaud, Georgina Pappas, Ye Chen, Eric Maudlin-Jeronimo, Richard McCarron,