Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8841383 | Neuroscience Letters | 2018 | 6 Pages |
Abstract
We examined the CIS ratio for nine AD patients, nine DLB patients, eight patients with MCI-AD, and nine patients with MCI-DLB using FDG PET and IMP SPECT. The CIS ratio was calculated as the total count density for the mid-posterior cingulate cortex divided by the total count density for the precuneus and cuneus using the stereotactic extraction estimation method. In the dementia groups, receiver operating characteristic analysis of the CIS ratio showed signiï¬cant accuracy for differentiating between AD and DLB on both FDG PET and IMP SPECT. In the MCI groups, only the FDG PET-derived CIS ratio displayed signiï¬cant accuracy for differentiating between AD and DLB. A larger study is needed to replicate these findings.
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Authors
Yuhei Chiba, Hiroshige Fujishiro, Eizo Iseki, Koji Kasanuki, Kiyoshi Sato,