Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8841981 | Neuroscience Letters | 2018 | 9 Pages |
Abstract
Upregulation of miR-215 exerts neuroprotection against ischemic injury by negatively regulating Act1/IL-17 receptor A signaling. These findings provide potential therapeutic targets for the treatment of ischemic stroke.
Keywords
JnkUTRhuman embryonic kidney 293TMEKK1Act1IL-17RATRAFN2a cellHEK293TMCAOMCAICAECATTCFITCNF-kBCCAOGD/RIschemic injurymiddle cerebral artery occlusionTriphenyl Tetrazolium ChlorideTIRmiddle cerebral arteryexternal carotid arteryinternal carotid arterycommon carotid arterytumor necrosis factor receptor-associated factornuclear factor kappa Bfluorescein isothiocyanateuntranslated regionmapmitogen-activated proteinPropidium iodide
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Authors
Hongxue Sun, Di Zhong, Jing Jin, Qingqing Liu, Haining Wang, Guozhong Li,