Progressing neurobiological strategies against proteostasis failure: Challenges in neurodegeneration

Article ID	Journal	Published Year	Pages	File Type
8842202	Progress in Neurobiology	2017	104 Pages	PDF

Keywords

ABC AMPK PDI Sirt1 NSAIDS PI3K TOR RAC MALDI-TOF mRNA CMA flavin adenine dinucleotide CDC SUMO ERAD NADPH NAC Aβ mTOR Hsc70 HSP90 Mcl-1 HSR CLPP hsp70 MIPS APP DIP RES IGF-1 PINK1 GPCR CFTR UPR ATG IRE1 LC3 SOD1 17-AAG HSF1 SCF TTR HspB8 MAO-B TRAF6 GRP78 RNPs AAA Macroautophagy Atg8 autophagy related gene ITRAQ AQUA MTB HSV-1 NOX4 CPDA GRP94 Hsp40 ABCE1 HDM2 HDAC6 USP NF-κβ OGG1 XBP-1 MuRF1 MutY Homolog DNA-PK PARP1 BCR-ABL Carboxyl terminus of Hsc70-interacting protein chaperone mediated autophagy NDDS sHSPs TSC2 Ubiquitin specific protease BAG3 OMM HRD1 HEWL RML Hsp100 tdp43 HtrA2 SIAH2 CRBN CDC48 PEDro Derlin-1 eIF2alpha Heat shock protein 40 Ribonucleoproteins Amfr Hsp26 gp78 MGRN1 PROTACS TAR DNA binding protein 43 serine/threonine-protein kinase 17-N-allylamino-17-demethoxygeldanamycin transthyretin Mahogunin Ring Finger 1 PQC Rocky Mountain Laboratory protein kinase-like endoplasmic reticulum kinase 8-oxoguanine DNA glycosylase AMP-activated protein kinase ataxia-telangiectasia mutated ATPases associated with diverse cellular activities BiP cAMP Cbl-b Cereblon DUBs ERKs G-protein-coupled receptor MAPK MAPK/ERK kinase NADPH oxidase 4 PTEN-induced putative kinase 1 messenger RNA ROS Cyclic adenosine monophosphate inositol-requiring enzyme 1 Deubiquitinating enzymes Akt iPod AIF amyotrophic lateral sclerosis γ-aminobutyric acid Oleic acid docosahexaenoic acid difference gel electrophoresis muscle RING finger 1 Bax amyloid beta FAD BAD isobaric tag for relative and absolute quantification Alzheimer's disease ALS Huntington's disease Neurodegenerative diseases Parkinson's disease hen egg white lysozyme Endoplasmic reticulum associated degradation Neurodegeneration CHOP forkhead Box O CASA ATM nonsteroidal anti-inflammatory drug DHA DIGE Resveratrol cystic fibrosis transmembrane conductance regulator matrix-assisted laser desorption ionization time-of-flight electron transport chain light chain 3 Aging superoxide dismutase 1 Ubiquitin proteasome system SILAC endoplasmic reticulum heat shock cognate 70 Mass spectrometry eukaryotic translation initiation factor apoptosis inducing factor pharmacological agents outer mitochondrial membrane Heat shock transcription factor 1 TNF receptor associated factor 6 nuclear factor kappa B FoxO Natural products phosphatidylinositol-3-kinase Myeloid cell leukemia 1 Mycobacterium tuberculosis MEK nascent polypeptide-associated complex monoamine oxidase B stable isotope labeling by amino acids in cell culture nicotinamide adenine dinucleotide phosphate target of rapamycin Histone deacetylase 6 ETc DNA-dependent protein kinase HIV human immunodeficiency virus Herpes simplex virus-1 Heat shock response Unfolded protein response Palmitic acid Database of Interacting Proteins Proteostasis Bcl-2 Associated X protein X-box binding protein 1 Binding immunoglobulin Protein glucose-regulated protein 94 protein disulfide isomerase heat shock protein 70 Heat shock protein 90 CCAAT-enhancer-binding protein homologous protein amyloid precursor protein Small heat shock proteins mitogen-activated protein kinase PERK Cell division cycle CHiP CaP quality control Mitochondrial quality control Protein quality control Absolute quantification ATP-binding cassette Extracellular signal–regulated kinases GABA glucose regulated protein 78 Reactive oxygen species Autocrine motility factor receptor UPS

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Progressing neurobiological strategies against proteostasis failure: Challenges in neurodegeneration

Authors

Ayeman Amanullah, Arun Upadhyay, Vibhuti Joshi, Ribhav Mishra, Nihar Ranjan Jana, Amit Mishra,