Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8842429 | Hearing Research | 2018 | 15 Pages |
Abstract
In addition, significant pair-wise correlations were observed among questionnaire variables, metabolite variables, questionnaire-metabolite variables, and metabolite-loudness variables. As part of this correlation analysis, we demonstrate for the first time that active rTMS produced a down regulation in the excitatory neurotransmitter glutamate that was highly correlated (r = 0.77, p < 0.05) with a reduction in tinnitus loudness levels measured psychoacoustically with a magnitude estimation procedure. Overall, this study provides unique information on neurochemical, psychoacoustic, and questionnaire-related profiles which emphasizes the emerging fields of perceptual and cognitive MRS and provides a perspective on a new frontier in auditory and tinnitus-related research.
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Neuroscience
Sensory Systems
Authors
Anthony T. Cacace, Jiani Hu, Stephen Romero, Yang Xuan, Robert F. Burkard, Richard S. Tyler,