Is a transdisciplinary perspective on economic complexity possible?

Marshall's problem regarding the relationship between economics and physics and biology is considered within the context of the possibility of a transdisciplinary approach that would truly combine the various disciplines. While a combined econophysics is very much an ongoing enterprise, and a possible econobiology may be emerging along several different lines, a full combination of all three is not in sight except possibly in the area of global climate-economy modeling. It is argued that heterogeneous interacting agent forms of complexity are likely to provide the best methods for achieving such transdisciplinary models.