Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8855353 | Environment International | 2018 | 10 Pages |
Abstract
While HHcys and decreased %DMA were associated with increased risk for skin lesions, and MTHFR 677 Câ¯ââ¯T was a strong predictor of HHcys, MTHFR 677 Câ¯ââ¯T was not associated with skin lesion risk. Future studies should explore (i) non-OCM and non-genetic determinants of Hcys and (ii) if genetic findings are replicated in other As-exposed populations, mechanisms by which OCM SNPs may influence the dose-dependent effects of As on skin lesion risk.
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Environmental Science
Environmental Chemistry
Authors
Megan M. Niedzwiecki, Xinhua Liu, Huiping Zhu, Megan N. Hall, Vesna Slavkovich, Vesna Ilievski, Diane Levy, Abu B. Siddique, Muhammad G. Kibriya, Faruque Parvez, Tariqul Islam, Alauddin Ahmed, Ana Navas-Acien, Joseph H. Graziano, Richard H. Finnell,