| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8856780 | Environmental Pollution | 2018 | 11 Pages |
Abstract
Mechanism for GSPE ameliorating lead-induced liver metabolic disturbance. In rat liver, lead induced fatty acids metabolic dysfunction via oxidative stress-mediated inhibition of PPARα signaling pathway. However, GSPE maintained fatty acid metabolic homeostasis through abolishing lead-induced suppression of PPARα signaling pathway.198
Keywords
RXRALTRNSiNOSGSPEPPARαRetinoid X receptorGSHPBASCD1stearoyl-CoA desaturase-1FABP1GO analysisMDAPBSROST-choASTAspartate aminotransferaseAlanine aminotransferaseperoxisome proliferator-activated receptor alphaLead acetateGene ontology analysistriglycerideTranscriptional regulationKEGG یا Kyoto Encyclopedia of Genes and Genomes Kyoto Encyclopedia of Genes and GenomesSODLeadinducible nitric oxide synthaseSuperoxide dismutaseGrape seed proanthocyanidin extractmalondialdehydePhosphate-buffered salinetotal cholesterolGlutathioneReactive oxidative species
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Authors
Daqian Yang, Huijie Jiang, Jingjing Lu, Yueying Lv, Ruiqi Baiyun, Siyu Li, Biying Liu, Zhanjun Lv, Zhigang Zhang,