Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive

Article ID	Journal	Published Year	Pages	File Type
8860603	Science of The Total Environment	2018	18 Pages	PDF

Keywords

FET PPARγ WFD TCDD DWTP HC5 NOEC Fish embryo toxicity ACR no observed adverse effect levels EEQ MIE EQS MOA EBT PXR NOAEL EBM SPE POD PAH PCB MEC WWTP LID AHR Extrapolation factor Guideline value Bioassay Environmental quality standard Solid-phase extraction Reporter gene assay Polychlorinated biphenyls Wastewater treatment plant Mode of action Water Framework Directive molecular initiating event Risk quotient Mixture toxicity Whole effluent toxicity Risk index Effect concentration measured environmental concentration REF Wet Acute-to-chronic ratio Water quality monitoring Point of departure Thyroid hormone Polycyclic aromatic hydrocarbons Toxic unit Drinking water treatment plant arylhydrocarbon receptor Androgen Receptor Estrogen receptor Thyroid receptor Peroxisome proliferator activated receptor Progesterone receptor Pregnane X receptor glucocorticoid receptor

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Life Sciences Environmental Science Environmental Chemistry

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Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive

Authors

Beate I. Escher, Selim AÑt-AÑssa, Peter A. Behnisch, Werner Brack, François Brion, Abraham Brouwer, Sebastian Buchinger, Sarah E. Crawford, David Du Pasquier, Timo Hamers, Karina Hettwer, Klára Hilscherová, Henner Hollert, Robert Kase,