| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8918976 | Current Opinion in Biomedical Engineering | 2018 | 8 Pages |
Abstract
This schematic displays various biophysical cues that can be used during the differentiation of human pluripotent stem cells to yield specific vascular cell types. The goal is that these biomechanical cues used during differentiation will result in cells with the functional characteristics necessary for withstanding the physiological environment. This will then allow us to engineer complex tissues tailored for patient-specific therapies.200
Keywords
Vascular differentiationKDRPDMSVSMCsHPSCshiPSCsCXCR4hESCsECMECsYAPHuman induced pluripotent stem cellshuman embryonic stem cellsHuman pluripotent stem cellsVascular smooth muscle cellsSmooth muscle cellsEndothelial cellsExtracellular matrixC-X-C chemokine receptor type 4yes-associated proteinPolydimethylsiloxanevascular endothelial cadherinkinase insert domain receptor
Related Topics
Physical Sciences and Engineering
Engineering
Biomedical Engineering
Authors
Xin Yi Chan, Joon H. Eoh, Sharon Gerecht,