| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8921788 | Frontiers in Laboratory Medicine | 2017 | 4 Pages |
Abstract
MicroRNAs (miRNAs), a class of non-coding single small RNAs transcribed from Eukaryotic genes, regulate gene expression at post-transcriptional levels via binding to 3â²-untranslation region (3â² UTR) inducing translation inhibition or mRNA degradation of their targets. MiR-590 plays a key role in cellular proliferation, differentiation, apoptosis and aging, and participates in development and progress of many diseases including cancer. Furthermore, miR-590 has different functions as a tumor suppressor or an oncogene by targeting various genes. This review is to summarize the structure, biological function and role of the miR-590 gene.
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Authors
Yang Dong, Guang-Bin Qiu,