Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8922628 | EndocrinologÃa, Diabetes y Nutrición | 2017 | 7 Pages |
Abstract
Recently, there have been advances in understanding of the changes that occur in the hypothalamic-pituitary-adrenal axis during the different stages of critical disease. Such advances have led to a paradigm change, so that the aforementioned adaptations are no longer considered the result of adrenal axis activation, but a consequence of decreased cortisol metabolism illness. Knowledge of this new pathophysiological bases should lead to reconsider the diagnosis and treatment of adrenal insufficiency in critically ill patients, a condition poorly understood to date.
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Authors
Laura Mateos Moreno, Nuria Palacios GarcÃa, Francisco Javier Estrada GarcÃa,