Acute antidepressant effects of deep brain stimulation - Review and data from slMFB-stimulation

Acute changes in symptoms of depression can be measured with DACS. To assess the predictive value of acute effects for long-term outcome a larger sample is needed. The systematic assessment of acute antidepressant effects can help to optimize stimulation parameters in DBS studies. The predictive value of key symptoms of depression for the response to a treatment and for individually shaped treatment relies on assessment tools for acute effects in depression. Because of the high interest of this topic, we provide a comprehensive review of the literature on acute effects of DBS for depression.