Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8930034 | British Journal of Anaesthesia | 2017 | 8 Pages |
Abstract
We developed a behavioural model in mice that enabled characterization of sevoflurane-induced hyperactivity. The kainate (GluK2) receptor antagonist attenuated these sevoflurane-induced hyperactivities in vivo, suggesting that kainate receptors might be the underlying therapeutic targets for sevoflurane-induced hyperactivities in general anaesthesia.
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Authors
P. Liang, F. Li, J. Liu, D. Liao, H. Huang, C. Zhou,