Article ID Journal Published Year Pages File Type
8931679 British Journal of Anaesthesia 2015 10 Pages PDF
Abstract
Isoflurane stabilises the fast-inactivated state of neuronal Nav leading to greater depression of INa during high-frequency stimulation, consistent with enhanced inhibition of fast firing neurones.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Anesthesiology and Pain Medicine
Preview
Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane
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