Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8932001 | British Journal of Anaesthesia | 2015 | 11 Pages |
Abstract
The addition of a linker between fentanyl and Dmt-Tic did not alter the ability to bind to MOP and DOP, however a substantial loss in MOP functional activity was apparent. This highlights the difficulty in multifunctional opioid development.
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Authors
M.F. Bird, R.S. Vardanyan, V.J. Hruby, G. Calò, R. Guerrini, S. Salvadori, C. Trapella, J. McDonald, D.J. Rowbotham, D.G. Lambert,