| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8932191 | British Journal of Anaesthesia | 2015 | 11 Pages |
Abstract
Methadone induces typical LA effects by inhibiting Na+ channels with a potency similar to that of bupivacaine. This hitherto unknown property of methadone might contribute to its high efficacy when applied as an adjuvant to LA.
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Authors
C. Stoetzer, K. Kistner, T. Stüber, M. Wirths, V. Schulze, T. Doll, N. Foadi, F. Wegner, J. Ahrens, A. Leffler,