| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8934342 | British Journal of Anaesthesia | 2012 | 8 Pages |
Abstract
Benzodiazepine tolerance can worsen ischaemic neuronal injury and abolish the neuroprotection provided by post-ischaemic diazepam. Pre-treatment with flumazenil treatment reversed benzodiazepine tolerance and restored neuroprotection by post-ischaemic diazepam. These findings may suggest that management of patient's risk of developing cerebral ischaemia may need to take into account current use.
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Authors
M. Iwata, S. Inoue, M. Kawaguchi, H. Furuya,