Article ID Journal Published Year Pages File Type
8934503 British Journal of Anaesthesia 2012 11 Pages PDF
Abstract
Morphine preconditioning protects against IRI in both normal and cirrhotic rat liver. This involves opioid receptors, phosphatidylinositol-3-kinase, and Akt. The downstream pathways involved are different for cirrhotic liver, with preliminary evidence suggesting involvement of HO-1.
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Health Sciences Medicine and Dentistry Anesthesiology and Pain Medicine
Preview
Pretreatment with intrathecal or intravenous morphine attenuates hepatic ischaemia-reperfusion injury in normal and cirrhotic rat liver
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