Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8934588 | British Journal of Anaesthesia | 2012 | 9 Pages |
Abstract
Sevoflurane at concentrations of â¥2% significantly inhibits the SOCE activity and prevents the resultant cellular Ca2+ overload that leads to hypercontracture in ventricular myocytes. This inhibitory action may be involved in the cardioprotective effect of sevoflurane against Ca2+ overload-mediated injury.
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Authors
A. Kojima, H. Kitagawa, M. Omatsu-Kanbe, H. Matsuura, S. Nosaka,