Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8935231 | British Journal of Anaesthesia | 2012 | 9 Pages |
Abstract
We have shown in a range of preparations and assays that UFP-505 behaves as a potent MOP agonist and DOP antagonist; a MOP/DOP bifunctional opioid. Further studies in dual expression systems and whole animals with this prototype are warranted.
Keywords
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Authors
N. Dietis, J. McDonald, S. Molinari, G. Calo, R. Guerrini, D.J. Rowbotham, D.G. Lambert,