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Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice

Article ID Journal Published Year Pages File Type
8936282 British Journal of Anaesthesia 2010 7 Pages PDF
Abstract
Our results suggest that TRPV1 antagonists can be used adjunctively to morphine treatment because they strengthen morphine antinociception and prevent the development of tolerance, and also physical dependence, on morphine.
Keywords
Hot-plate testWithdrawal symptomsmorphinetransient receptor potential vanilloid type 1capsazepine
Related Topics
Health Sciences Medicine and Dentistry Anesthesiology and Pain Medicine
Preview
Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice
Authors
T.-L. Nguyen, Y.-S. Nam, S.-Y. Lee, H.-C. Kim, C.-G. Jang,
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Journal
British Journal of Anaesthesia
Journal: British Journal of Anaesthesia
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