| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8936381 | British Journal of Anaesthesia | 2010 | 9 Pages |
Abstract
We have derived a population PK model using obese and non-obese data to characterize propofol PK over a wide range of body weights. An allometric model using TBW as the size descriptor of volumes and clearances was superior to other size descriptors to characterize propofol PK in obese patients.
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Authors
L.I. CortÃnez, B.J. Anderson, A Penna, L Olivares, H.R. Muñoz, N.H.G. Holford, M.M.R.F. Struys, P Sepulveda,