Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8936466 | British Journal of Anaesthesia | 2010 | 5 Pages |
Abstract
Propofol requirement to maintain hypnosis during general anaesthesia appears to decrease with deterioration in the cognitive status in the elderly. We suggest that a cognitive dysfunction linked to a cerebral cholinergic dysfunction may influence the brain sensitivity for propofol in aged patients.
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Authors
F.-Z. Laalou, M Egard, M Guillot, E Noll, G Taglang, L Pain,