Monitoring of the responsiveness to noxious stimuli during sevoflurane mono-anaesthesia by using RIII reflex threshold and bispectral index

All three instruments can be used for a prediction of movement responses to a noxious stimulus under sevoflurane mono-anaesthesia with an accuracy exceeding prediction by chance. The accuracy of the BIS to predict these responses appears to be lower compared with the RIII reflex threshold or the end-tidal sevoflurane concentration.