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Study of the time course of the clinical effect of propofol compared with the time course of the predicted effect-site concentration: performance of three pharmacokinetic-dynamic models

Article ID Journal Published Year Pages File Type
8936780 British Journal of Anaesthesia 2010 7 Pages PDF
Abstract
Targeting CePROP at which patients lose consciousness with effect-site-controlled TCI does not translate into an immediate constant effect.
Keywords
model, pharmacodynamicdrug delivery, computerizedpharmacology, propofolmodel, pharmacokineticmonitoring, depth of anaesthesia
Related Topics
Health Sciences Medicine and Dentistry Anesthesiology and Pain Medicine
Preview
Study of the time course of the clinical effect of propofol compared with the time course of the predicted effect-site concentration: performance of three pharmacokinetic-dynamic models
Authors
M. Coppens, J.G.M. Van Limmen, T. Schnider, B. Wyler, S. Bonte, F. Dewaele, M.M.R.F. Struys, H.E.M. Vereecke,
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Journal
British Journal of Anaesthesia
Journal: British Journal of Anaesthesia
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model, pharmacodynamic
drug delivery, computerized
pharmacology, propofol
model, pharmacokinetic
monitoring, depth of anaesthesia
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