Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8936881 | British Journal of Anaesthesia | 2010 | 8 Pages |
Abstract
Pravastatin improved NOS III-mediated vessel relaxation and exerted anti-inflammatory effects within the microcirculation after LPS administration in rats. Pravastatin therefore appears to have beneficial effects during sepsis, as a result of increased microvascular expression and function of NOS III.
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Authors
C.C. McGown, N.J. Brown, P.G. Hellewell, C.S. Reilly, Z.L.S. Brookes,