| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8937046 | British Journal of Anaesthesia | 2009 | 8 Pages |
Abstract
All commonly used local anaesthetics induce neuronal apoptosis in clinically used concentrations. The neurotoxicity correlates with lipid solubility and thus with the conduction blocking potency of the local anaesthetic, but is independent of the chemical class (ester/amide).
Keywords
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Authors
R. Werdehausen, S. Fazeli, S. Braun, H. Hermanns, F. Essmann, M.W. Hollmann, I. Bauer, M.F. Stevens,