| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8937187 | British Journal of Anaesthesia | 2009 | 9 Pages |
Abstract
We demonstrated increased opioid requirement for alfentanil in patients with the G118 SNP, who self-administered a higher dose, achieved higher plasma concentration, and yet complained of more severe pain. This observation suggests that G118 SNP impairs the analgesic response to opioids.
Related Topics
Health Sciences
Medicine and Dentistry
Anesthesiology and Pain Medicine
Authors
Y. Ginosar, E.M. Davidson, Y. Meroz, S. Blotnick, M. Shacham, Y. Caraco,