Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8937661 | British Journal of Anaesthesia | 2009 | 10 Pages |
Abstract
This study shows that S-(+)-ketamine can induce apoptotic insults to human HepG2 cells via a Bax-mitochondria-caspase protease pathway. Thus, we suggest that S-(+)-ketamine at a clinically relevant or an abused concentration may induce liver dysfunction possibly due to its toxicity to hepatocytes.
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Authors
S.-T. Lee, T.-T. Wu, P.-Y. Yu, R.-M. Chen,