| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8938051 | British Journal of Anaesthesia | 2008 | 7 Pages |
Abstract
We demonstrate, for the first time, that the human antimicrobial peptide, LL-37, induces endothelium-dependent relaxation in human omental veins mediated via an effect on endothelial ALX. The relaxation involves the release of nitric oxide and EDHF but not prostanoids. LL-37 released from white blood cells could contribute to blood vessel dilatation during sepsis and treatment with ALX antagonists might be successful.
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Authors
I. Berkestedt, A. Nelson, M. Bodelsson,