Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8938929 | British Journal of Anaesthesia | 2007 | 10 Pages |
Abstract
Repeated administration of HES 130/0.42 shows no accumulation and fewer tendencies to time-dependent changes in pharmacokinetic parameters than HES 200/0.5. The improved reproducibility may improve drug safety, particularly as the accumulation of residual starch with HES 200/0.5 does not contribute to the colloid's volume effect, but may rather increase the risk of undesired reactions.
Keywords
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Authors
G.B. Lehmann, F. Asskali, M. Boll, M.A. Burmeister, G. Marx, R. Hilgers, H. Förster,