Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8939481 | British Journal of Anaesthesia | 2006 | 7 Pages |
Abstract
Preoxygenation had a substantial effect on the speed of early desaturation, but less effect on the time for
SaO2 to decrease from 90 to 40%. Preoxygenation substantially delayed dangerous desaturation in all age groups, although the rapidity of denitrogenation in the very young (caused by the large ratio of minute ventilation to functional residual capacity) resulted in lengthy preoxygenation having little benefit over brief preoxygenation. Airway obstruction during apnoea accelerated every child's hypoxaemia through prevention of mass flow addition to oxygen stores and through intrathoracic depressurization. On average, haemoglobin desaturation from
SaO2 90 to 40% was 33% minâ1 with an obstructed airway and 26% minâ1 with an open airway; all ages were similarly susceptible to this effect.
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Authors
J.G. Hardman, J.S. Wills,