Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8939633 | British Journal of Anaesthesia | 2006 | 6 Pages |
Abstract
While buprenorphine's analgesic effect increased significantly, respiratory depression was similar in magnitude and timing for the two doses tested. We conclude that over the dose range tested buprenorphine displays ceiling in respiratory effect but none in analgesic effect.
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Authors
Dahan A., Yassen A., Romberg R., Sarton E., Teppema L., Olofsen E., Danhof M.,