| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8940961 | Journal of EuCornea | 2018 | 7 Pages |
Abstract
Results demonstrated that chitosan is taken up into conjunctival epithelial cells in vitro and in vivo, therefore fulfilling some of the requirements of an adjuvant for conjunctival mucosal vaccines. C-NAC is also well tolerated but not taken up by cells, making it a good candidate for ocular formulations supposed to persist on the ocular surface for an extended period of time.
Keywords
fluorescein-isothiocyanatePBS4′,6-diamidin-2-phenylindoleFITCTEERDAPIH&EEDTAethylene-diamine-tetra-acetic acidDESstandard deviationDrug deliveryUptakeConjunctival epithelial cellsdry eye syndromePhosphate buffered salineBABlactate dehydrogenaseLDHtransepithelial electrical resistanceHematoxylin and EosinMolecular weightChitosan
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Authors
Nadine Schuerer, Elisabeth Stein, Aleksandra Inic-Kanada, Ehsan Ghasemian, Marijana Stojanovic, Jacqueline Montanaro, Nora Bintner, Christine Hohenadl, Robert Sachsenhofer, Talin Barisani-Asenbauer,