| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8945216 | Gynecologic Oncology | 2018 | 10 Pages |
Abstract
Detecting pathogenic mutations in 13/50 genes examined at comparable frequencies in hrHPV(+) and hrHPV(â) tumors suggest that genetic mechanisms of the two routes of VSCC pathogenesis may be similar, despite being initiated from different premalignant lesions. Importantly, our data provide a rationale for new anti-VSCC therapies targeting the PI3K/AKT/mTOR pathway.
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Authors
Sebastian ZiÄba, Artur Kowalik, Kamil Zalewski, Natalia Rusetska, Krzysztof Goryca, Agata PiaÅcik, Marcin Misiek, Elwira BakuÅa-Zalewska, Janusz KopczyÅski, Kamil Kowalski, Jakub Radziszewski, Mariusz BidziÅski, StanisÅaw Góźdź,