| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8949951 | Pathology - Research and Practice | 2018 | 22 Pages |
Abstract
Long non-coding RNAs (lncRNAs), are lengthy noncoding transcripts with pivotal roles in biological pathways including cell cycle, apoptosis and chromatin remodeling. Aberrant expression of lncRNAs has been strongly connected with tumor progression and metastasis. However, the prognostic significance of lncRNAs in diffuse large-B-cell lymphoma (DLBCL) remains unclear. In this study, the expression levels of 189 approved lncRNAs were considered in DLBCL patients using several different genomic and transcriptome datasets. The analyses showed that the lncRNA GAS5 allocated the maximum score of RNA dysregulation and can be considered as good choice in DLBCLs' researches.
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Authors
Fatemeh Dousti, Arman Shahrisa, Hossein Ansari, Mohammadreza Hajjari, Yaser Tahmasebi Birgani, Javad Mohammadiasl, Maryam Tahmasebi Birgani,